Structure-activity Study of Bacteriostatic Kojic Acid Analogs
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چکیده
منابع مشابه
Kojic Acid Derivatives
Melanin is one of the most important pigments which exist ubiquitously from microorganisms to plants and animals. It is secreted by melanocyte cells and determines the color of skin and hair in mammalians. It protects the skin from photocarcinogenesis by absorbing UV sunlight and removing reactive oxygen species (ROS) (Gupta, 2006; Kim, 2005; Sapkota, 2011). It is formed by enzymatically cataly...
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Barker, S. B., Kiely, C. E., Dirks, H. B., Klitgaard, H. M., Wang, S. C. & Wawzonek, S. (1950). J. Phlarmacol. 99, 202. Barnes, J. H., Elks, J., Stephens, F. F. & Waller, G. J. (1953). J. chem. Soc. p. 764. Cortell, R. E. (1949). J. clin. Endocrin. 9, 955. Datta, R. L. & Prosad, N. (1917). J. Amer. chem. Soc. 39, 443. Frieden, E. & Winzler, R. J. (1949). J. biol. Chem. 179, 423. Kalb, L., Schwe...
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The relationship between the activity and the chemical structure of cadeguomycin (CDM, 7-carboxy-7-deazaguanosine) was studied with six analogs of CDM. Both activities of CDM, enhancing the incorporation of [3H]thymidine in K562 cells and potentiating the cytotoxicity of cytosine arabinoside for K562 cells, were significantly augmented by the replacement of the 7-carboxyl group with cyano (CDM-...
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prepared by stirring a mixture of 1 with the corresponding carboxylic acid (1.1 equiv.) in the presence of dicyclohexylcarbodiimide (DCC) (1.1 equiv.) and 4-dimethylaminopyridine (DMAP) (0.1 equiv.) in CH2Cl2 at room temperature for 24 hours. The crude products, obtained after usual work up, were purified by preparative TLC on silica gel (Article No. 13794, E. Merck) using CHCl3 MeOH (9:1) as t...
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Cybulska, Janina (State Institute of Hygiene, Warsaw, Poland), and J. Jeljaszewicz. Bacteriostatic activity of serum against staphylococci. J. Bacteriol. 91:953-962. 1966.-Antistaphylococcal activity of normal serum against strains exhibiting various patterns of coagulase, clumping-factor, and staphylokinase production is not connected with the presence of these factors. Purified coagulase does...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1975
ISSN: 0002-1369
DOI: 10.1080/00021369.1975.10861774